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KMID : 0359319780180010001
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Korean Journal of Veterinary Research
1978 Volume.18 No. 1 p.1 ~ p.7
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Clinical , Hematological and Blood Chemical Changes in Korean Native Goats Following Administration of Combelen
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Abstract
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In order to detect the clinical effect of combelen which is used for sedation of domestic animals, 10 heads of clinically healthy Korean native goats were used in this study.
They were divided into two groupss one is dose level of 1㎖ per 10㎏ of body weight with 1% combelen and the other is dose level of 3 ㎖.
Clinical observations and changes in blood components after administration of combelen were made.
1. There was no adverse effect due to combelen, but sodative effect was insufficient.
2. During sedative period the changes in heart rate and respiratory rate showed noticeable change, and body temperature was slightly decreased.
3. In ECG recordings, except for slight changes in T wave, significant change was not observed.
4. Erythrocytes, leukocytes, hemoglobin concentration and packed cell volume showed tendency to decrease during the period of sedation.
5. SGOT activity showed a remarkable increase and BUN showed a great decrease 24 hours after administration in the group of 3㎖/10㎏. Blood glucose levee increased during the period of sedation in both groups.
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